Erythromycin Restores Osteoblast Differentiation and Osteogenesis Suppressed by <i>Porphyromonas gingivalis</i> Lipopolysaccharide

• Main Authors: Hikaru Tamura (Author), Tomoki Maekawa (Author), Hisanori Domon (Author), Kridtapat Sirisereephap (Author), Toshihito Isono (Author), Satoru Hirayama (Author), Takumi Hiyoshi (Author), Karin Sasagawa (Author), Fumio Takizawa (Author), Takeyasu Maeda (Author), Yutaka Terao (Author), Koichi Tabeta (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The macrolide erythromycin (ERM) inhibits excessive neutrophil accumulation and bone resorption in inflammatory tissues. We previously reported that the expression of developmental endothelial locus-1 (DEL-1), an endogenous anti-inflammatory factor induced by ERM, is involved in ERM action. Furtherm...