Preclinical Evaluation of a Lead Specific Chelator (PSC) Conjugated to Radiopeptides for ²⁰³Pb and ²¹²Pb-Based Theranostics

• Autores principales: Mengshi Li (Autor), Nicholas J. Baumhover (Autor), Dijie Liu (Autor), Brianna S. Cagle (Autor), Frédéric Boschetti (Autor), Guillaume Paulin (Autor), Dongyoul Lee (Autor), Zhiming Dai (Autor), Ephraim R. Obot (Autor), Brenna M. Marks (Autor), Ibrahim Okeil (Autor), Edwin A. Sagastume (Autor), Moustafa Gabr (Autor), F. Christopher Pigge (Autor), Frances L. Johnson (Autor), Michael K. Schultz (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2023-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

²⁰³Pb and ²¹²Pb have emerged as promising theranostic isotopes for image-guided α-particle radionuclide therapy for cancers. Here, we report a cyclen-based Pb specific chelator (PSC) that is conjugated to tyr³-octreotide via a PEG&...