Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes

• Huvudupphovsmän: Vito Antonio Baldassarro (Författare, medförfattare), Alessandra Marchesini (Författare, medförfattare), Luciana Giardino (Författare, medförfattare), Laura Calzà (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: The Company of Biologists, 2017-05-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Microvascular dysfunction is considered an integral part of Alzheimer disease (AD) pathogenesis, but the possible relationship between amyloid pathology, microvascular dysfunction and cell death is still unclear. In order to investigate the influence of intraneuronal amyloid-β (Aβ) accumulation on v...