The Discovery of Insulin-Regulated Aminopeptidase (IRAP) Inhibitors: A Literature Review

• Main Authors: Dimitris Georgiadis (Author), Angeliki Ziotopoulou (Author), Eleni Kaloumenou (Author), Angelos Lelis (Author), Antonia Papasava (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Fag: article
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Insulin-Regulated Aminopeptidase (IRAP, EC 3.4.11.3) is a multi-tasking member of the M1 family of zinc aminopeptidases. Among its diverse biological functions, IRAP is a regulator of oxytocin levels during late stages of pregnancy, it affects cellular glucose uptake by trafficking of the glucose tr...