A quantitative way to estimate clinical off-target effects for human membrane brain targets in CNS research and development

• Main Authors: Geerts H (Author), Spiros A (Author)
• פורמט: ספר
• יצא לאור: Dove Medical Press, 2012-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Athan Spiros1, Hugo Geerts1,21In Silico Biosciences, Berwyn, PA, USA; 2School of Medicine, University of Pennsylvania, Philadelphia, PA, USAAbstract: Although many preclinical programs in central nervous system research and development intend to develop highly selective and potent molecules directed...