Involvement of the TNF-α/SATB2 axis in the induced apoptosis and inhibited autophagy of osteoblasts by the antipsychotic Risperidone

• Main Authors: Shuyao Zhang (Author), Wei He (Author), Aiguo Li (Author), Chengkuan Zhao (Author), Yun Chen (Author), Chengcheng Xu (Author), Qiuzhen Zhang (Author), Danling Zheng (Author), Meini Chen (Author), Haixiong Miao (Author), Yihui Huang (Author)
• Format: Book
• Published: BMC, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Risperidone, an atypical antipsychotic, impedes serotonin and dopamine receptor systems. Meanwhile, tumor necrosis factor-α (TNF-α) is known to participate in regulating osteoblast functions. Consequently, the current study aimed to investigate whether the influences of Risperido...