Importance of Toxicokinetics to Assess the Utility of Zebrafish Larvae as Model for Psychoactive Drug Screening Using Meta-Chlorophenylpiperazine (mCPP) as Example

• Main Authors: Krishna Tulasi Kirla (Author), Ksenia J. Groh (Author), Michael Poetzsch (Author), Rakesh Kumar Banote (Author), Julita Stadnicka-Michalak (Author), Rik I. L. Eggen (Author), Kristin Schirmer (Author), Thomas Kraemer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The number of new psychoactive substances (NPS) increases rapidly, harming society and fuelling the need for alternative testing strategies. These should allow the ever-increasing number of drugs to be tested more effectively for their toxicity and psychoactive effects. One proposed strategy is to c...