Decreased angiotensin receptor 1 expression in ± AT1 Knockout mice testis results in male infertility and GnRH reduction

• Main Authors: Fangfang Zhao (Author), Yun Zou (Author), Hui Li (Author), Yaheng Zhang (Author), Xuele Liu (Author), Xuehao Zhao (Author), Xinyi Wu (Author), Wenyi Fei (Author), Ziling Xu (Author), Xuejun Yang (Author)
• Format: Book
• Published: BMC, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This study aimed to detect the effect of angiotensin receptor 1 (AT1) knock out (KO) on spermatogenesis and hypothalamic-pituitary-gonadal (HPG) axis hormone expression. Methods Normal C57BL/6 male mice were used as control group or treated with angiotensin receptor blocker, in a...