Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

• প্রধান লেখক: Mica Ohara-Imaizumi (লেখক), Kyota Aoyagi (লেখক), Toshihisa Ohtsuka (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2019-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca2+-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; however...