Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

• Asıl Yazarlar: Mica Ohara-Imaizumi (Yazar), Kyota Aoyagi (Yazar), Toshihisa Ohtsuka (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2019-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca2+-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; however...