Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

• Những tác giả chính: Mica Ohara-Imaizumi (Tác giả), Kyota Aoyagi (Tác giả), Toshihisa Ohtsuka (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2019-09-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca2+-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; however...