Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish

• Main Authors: Karishma Chhabria (Author), Avgoustinos Vouros (Author), Caroline Gray (Author), Ryan B. MacDonald (Author), Zhen Jiang (Author), Robert Neil Wilkinson (Author), Karen Plant (Author), Eleni Vasilaki (Author), Clare Howarth (Author), Timothy J. A. Chico (Author)
• Format: Book
• Published: The Company of Biologists, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes is associated with dysfunction of the neurovascular unit, although the mechanisms of this are incompletely understood and currently no treatment exists to prevent these negative effects. We previously found that the nitric oxide (NO) donor sodium nitroprusside (SNP) prevents the detrimental...