Protein PEGylation for the design of biobetters: from reaction to purification processes

Protein PEGylation for the design of biobetters: from reaction to purification processes

The covalent attachment of polyethylene glycol (PEG) to therapeutical proteins is an important route to develop biobetters for biomedical, biotech and pharmaceutical industries. PEG conjugation can shield antigenic epitopes of the protein, reduce degradation by proteolytic enzymes, enhance long-term...

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Main Authors: João Henrique Picado Madalena Santos (Author), Karin Mariana Torres-Obreque (Author), Giovanna Pastore Meneguetti (Author), Beatriz Panichi Amaro (Author), Carlota Oliveira Rangel-Yagui (Author)
Format: Book
Published: Universidade de São Paulo, 2018-11-01T00:00:00Z.
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