Digital imaging-assisted quantification of H3K27me3 immunoexpression in luminal A/B-like, HER2-negative, invasive breast cancer predicts patient survival and risk of recurrence

• Main Authors: Mário Fontes-Sousa (Author), João Lobo (Author), Silvana Lobo (Author), Sofia Salta (Author), Maria Amorim (Author), Paula Lopes (Author), Luís Antunes (Author), Susana Palma de Sousa (Author), Rui Henrique (Author), Carmen Jerónimo (Author)
• Format: Book
• Published: BMC, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Breast cancer (BC) is a major health concern and better understanding of its biology might improve treatment decisions and patient outcomes. Histone3 Lysine27 tri-methylation (H3K27me3) is a post-translational histone modification frequently associated with altered gene expressio...