Protective and Pathogenic Roles of CD8+ T Lymphocytes in Murine Orientia tsutsugamushi Infection.

• Main Authors: Matthias Hauptmann (Author), Julia Kolbaum (Author), Stefanie Lilla (Author), David Wozniak (Author), Mohammad Gharaibeh (Author), Bernhard Fleischer (Author), Christian A Keller (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

T cells are known to contribute to immune protection against scrub typhus, a potentially fatal infection caused by the obligate intracellular bacterium Orientia (O.) tsutsugamushi. However, the contribution of CD8+ T cells to protection and pathogenesis during O. tsutsugamushi infection is still unk...