Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC ^min/J Mice

• मुख्य लेखकों: Miriam Corrado (लेखक), Carmine Giorgio (लेखक), Elisabetta Barocelli (लेखक), Giuseppe Vittucci Marzetti (लेखक), Anna Maria Cantoni (लेखक), Rosanna Di Lecce (लेखक), Matteo Incerti (लेखक), Riccardo Castelli (लेखक), Alessio Lodola (लेखक), Massimiliano Tognolini (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The Eph receptors are the largest receptors tyrosine kinases (RTKs) family in humans and together with ephrin ligands constitute a complex cellular communication system often dysregulated in many tumors. The role of the Eph-ephrin system in colorectal cancer (CRC) has been investigated and different...