Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons

• Main Authors: Amanda Laque (Author), Sangho Yu (Author), Emily Qualls-Creekmore (Author), Sarah Gettys (Author), Candice Schwartzenburg (Author), Kelly Bui (Author), Christopher Rhodes (Author), Hans-Rudolf Berthoud (Author), Christopher D. Morrison (Author), Brenda K. Richards (Author), Heike Münzberg (Author)
• Format: Book
• Published: Elsevier, 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Leptin modulates food reward via central leptin receptor (LepRb) expressing neurons. Food reward requires stimulation of midbrain dopamine neurons and is modulated by central leptin action, but the exact central mechanisms remain unclear. Stimulatory and inhibitory leptin actions on dopam...