Rab35 GTPase positively regulates endocytic recycling of cardiac KATP channels

• Main Authors: Bo Yang (Author), Jia-Lu Yao (Author), Jian-Yi Huo (Author), Yu-Long Feng (Author), William A. Coetzee (Author), Guang-Yin Xu (Author), Hua-Qian Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ATP-sensitive K+ (KATP) channel couples membrane excitability to intracellular energy metabolism. Maintaining KATP channel surface expression is key to normal insulin secretion, blood pressure and cardioprotection. However, the molecular mechanisms regulating KATP channel internalization and endocyt...