Anti-Th17 and anti-Th2 responses effects of hydro-ethanolic extracts of Aframomum melegueta, Khaya senegalensis and Xylopia aethiopica in hyperreactive onchocerciasis individuals' peripheral blood mononuclear cells.

• Main Authors: Gnatoulma Katawa (Author), Essoham Ataba (Author), Manuel Ritter (Author), Oukoe Marthe Amessoudji (Author), Essimanam Rosalie Awesso (Author), Pélagie Edlom Tchadié (Author), Fagdéba David Bara (Author), Fekandine Victoire Douti (Author), Kathrin Arndts (Author), Tchadjobo Tchacondo (Author), Komlan Batawila (Author), Yaovi Ameyapoh (Author), Achim Hoerauf (Author), Simplice D Karou (Author), Laura E Layland (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperreactive onchocerciasis (HO) is characterized by a severe skin inflammation with elevated Th17-Th2 combined responses. We previously demonstrated the anthelminthic activity of Aframomum melegueta (AM), Xylopia aethiopica (XA) and Khaya senegalensis (KS) used by traditional healers to treat helm...