Defining stopping criteria for ending randomized clinical trials that investigate the interruption of transmission of soil-transmitted helminths employing mass drug administration.

• Main Authors: Marleen Werkman (Author), Jaspreet Toor (Author), Carolin Vegvari (Author), James E Wright (Author), James E Truscott (Author), Kristjana H Ásbjörnsdóttir (Author), Arianna Rubin Means (Author), Judd L Walson (Author), Roy M Anderson (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The current World Health Organization strategy to address soil-transmitted helminth (STH) infections in children is based on morbidity control through routine deworming of school and pre-school aged children. However, given that transmission continues to occur as a result of persistent reservoirs of...