BBSome ablation in SF1 neurons causes obesity without comorbidities

• Main Authors: Mohamed Rouabhi (Author), Deng-Fu Guo (Author), Donald A. Morgan (Author), Zhiyong Zhu (Author), Miguel López (Author), Leonid Zingman (Author), Justin L. Grobe (Author), Kamal Rahmouni (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: The hypothalamic ventromedial nucleus (VMH) plays a major role in metabolic control, but the molecular mechanisms involved remain poorly defined. We analyzed the relevance of the BBSome, a protein complex composed of 8 Bardet-Biedl syndrome (BBS) proteins including BBS1, in VMH steroidog...