Measuring the effects of macromolecular crowding on antibody function with biolayer interferometry

Biotherapeutic proteins are commonly dosed at high concentrations into the blood, which is an inherently complex, crowded solution with substantial protein content. The effects of macromolecular crowding may lead to an appreciable level of non-specific hetero-association in this physiological enviro...

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Main Authors: Dorothy M. Kim (Author), Xiao Yao (Author), Ram P. Vanam (Author), Michael S. Marlow (Author)
Format: Book
Published: Taylor & Francis Group, 2019-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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