Mitochondrial Metabolism as Target of the Neuroprotective Role of Erythropoietin in Parkinson's Disease

• Autori principali: Federica Rey (Autore), Sara Ottolenghi (Autore), Toniella Giallongo (Autore), Alice Balsari (Autore), Carla Martinelli (Autore), Robert Rey (Autore), Raffaele Allevi (Autore), Anna Maria Di Giulio (Autore), Gian Vincenzo Zuccotti (Autore), Serena Mazzucchelli (Autore), Roberta Foresti (Autore), Michele Samaja (Autore), Stephana Carelli (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Existing therapies for Parkinson's disease (PD) are only symptomatic. As erythropoietin (EPO) is emerging for its benefits in neurodegenerative diseases, here, we test the protective effect driven by EPO in in vitro (SH-SY5Y cells challenged by MPP⁺) and in vivo (C57BL/6J...