Methotrexate, an anti-inflammatory drug, inhibits Hepatitis E viral replication

• Main Authors: Akash Kumar (Author), Preeti Hooda (Author), Anindita Puri (Author), Radhika Khatter (Author), Mohammed S. Al-Dosari (Author), Neha Sinha (Author), Mohammad K. Parvez (Author), Deepak Sehgal (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatitis E Virus (HEV) is a positively oriented RNA virus having a 7.2 kb genome. HEV consists of three open reading frames (ORF1-3). Of these, ORF1 codes for the enzymes Methyltransferase (Mtase), Papain-like cysteine protease (PCP), RNA helicase, and RNA-dependent RNA polymerase (RdRp). Unavailab...