Methotrexate, an anti-inflammatory drug, inhibits Hepatitis E viral replication

• Autori principali: Akash Kumar (Autore), Preeti Hooda (Autore), Anindita Puri (Autore), Radhika Khatter (Autore), Mohammed S. Al-Dosari (Autore), Neha Sinha (Autore), Mohammad K. Parvez (Autore), Deepak Sehgal (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Hepatitis E Virus (HEV) is a positively oriented RNA virus having a 7.2 kb genome. HEV consists of three open reading frames (ORF1-3). Of these, ORF1 codes for the enzymes Methyltransferase (Mtase), Papain-like cysteine protease (PCP), RNA helicase, and RNA-dependent RNA polymerase (RdRp). Unavailab...