Methotrexate, an anti-inflammatory drug, inhibits Hepatitis E viral replication

• Главные авторы: Akash Kumar (Автор), Preeti Hooda (Автор), Anindita Puri (Автор), Radhika Khatter (Автор), Mohammed S. Al-Dosari (Автор), Neha Sinha (Автор), Mohammad K. Parvez (Автор), Deepak Sehgal (Автор)
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• Опубликовано: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Предметы: article
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Hepatitis E Virus (HEV) is a positively oriented RNA virus having a 7.2 kb genome. HEV consists of three open reading frames (ORF1-3). Of these, ORF1 codes for the enzymes Methyltransferase (Mtase), Papain-like cysteine protease (PCP), RNA helicase, and RNA-dependent RNA polymerase (RdRp). Unavailab...