Partial cross-protection between Japanese encephalitis virus genotype I and III in mice.

• Main Authors: Jianchao Wei (Author), Xin Wang (Author), Junjie Zhang (Author), Shuang Guo (Author), Linlin Pang (Author), Kun Shi (Author), Ke Liu (Author), Donghua Shao (Author), Yafeng Qiu (Author), Lihong Liu (Author), Frederik Widén (Author), Beibei Li (Author), Zhiyong Ma (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genotype III (GIII) Japanese encephalitis virus (JEV) predominance has gradually been replaced by genotype I (GI) over the last 20 years in many Asian countries. This genotype shift raises concerns about the protective efficacy of Japanese encephalitis (JE) vaccines, as all of the currently licensed...