Prerequisite Binding Modes Determine the Dynamics of Action of Covalent Agonists of Ion Channel TRPA1

• Autores principales: Balázs Zoltán Zsidó (Autor), Rita Börzsei (Autor), Erika Pintér (Autor), Csaba Hetényi (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2021-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Transient receptor potential ankyrin 1 (TRPA1) is a transmembrane protein channeling the influx of calcium ions. As a polymodal nocisensor, TRPA1 can be activated by thermal, mechanical stimuli and a wide range of chemically damaging molecules including small volatile environmental toxicants and end...