Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma

• Main Authors: Ida Cerqua (Author), Elisabetta Granato (Author), Angela Corvino (Author), Beatrice Severino (Author), Danilo D'Avino (Author), Martina Simonelli (Author), Elisa Perissutti (Author), Antonia Scognamiglio (Author), Davida Mirra (Author), Bruno D'Agostino (Author), Giuseppe Caliendo (Author), Antonietta Rossi (Author), Giuseppe Cirino (Author), Chiara Maria Motta (Author), Fiorentina Roviezzo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Hydrogen sulfide (H2S) is emerging as an important potential therapeutic option for respiratory inflammatory diseases. In this study, we investigated the effectiveness of a novel corticosteroid derivative, that is chemically linked to an H2S donor, in managing asthma features.Methods:...