Pharmacokinetics, safety, and tolerability of single and multiple doses of zuranolone in Japanese and White healthy subjects: A phase 1 clinical trial

• Main Authors: Takuhiro Sonoyama (Author), Ryosuke Shimizu (Author), Ryuji Kubota (Author), Yumiko Matsuo (Author), Daiki Okutsu (Author), Hideki Yamanaka (Author), Keiko Takasu (Author), Koichi Ogawa (Author), Tomoko Motomiya (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim This phase 1 study assessed the pharmacokinetics, safety, and tolerability of zuranolone in Japanese and White healthy adults, and Japanese healthy elderly subjects. Methods This single‐center study consisted of three parts. In Part A (randomized, double‐blind), the safety, tolerability...