Prior Antibiotic Therapy and the Onset of Healthcare-Associated Infections Sustained by Multidrug-Resistant <i>Klebsiella pneumoniae</i> in Intensive Care Unit Patients: A Nested Case-Control Study

• Main Authors: Giuseppe Migliara (Author), Valentina Baccolini (Author), Claudia Isonne (Author), Sara Cianfanelli (Author), Carolina Di Paolo (Author), Annamaria Mele (Author), Lorenza Lia (Author), Angelo Nardi (Author), Carla Salerno (Author), Susanna Caminada (Author), Vittoria Cammalleri (Author), Francesco Alessandri (Author), Guglielmo Tellan (Author), Giancarlo Ceccarelli (Author), Mario Venditti (Author), Francesco Pugliese (Author), Carolina Marzuillo (Author), Corrado De Vito (Author), Maria De Giusti (Author), Paolo Villari (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epidemiological research has demonstrated direct relationships between antibiotic consumption and the emergence of multidrug-resistant (MDR) bacteria. In this nested case-control study, we assessed whether prior exposure to antibiotic therapy and its duration affect the onset of healthcare-associate...