A single dose of the DENV-1 candidate vaccine rDEN1Δ30 is strongly immunogenic and induces resistance to a second dose in a randomized trial.

• Auteurs principaux: Anna P Durbin (Auteur), Stephen S Whitehead (Auteur), Donna Shaffer (Auteur), Dan Elwood (Auteur), Kimberli Wanionek (Auteur), Bhavin Thumar (Auteur), Joseph E Blaney (Auteur), Brian R Murphy (Auteur), Alexander C Schmidt (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2011-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Dengue is an emerging infectious disease that has become the most important arboviral infection worldwide. There are four serotypes of dengue virus, DENV-1, DENV-2, DENV-3, and DENV-4, each capable of causing the full spectrum of disease. rDEN1Δ30 is a live attenuated investigational vaccine for the...