Early Chronic Carbamazepine-in-Food Administration to MAM/Pilocarpine Rats Does Not Affect Convulsive Motor Seizures

• Main Authors: Paola Nobili (Author), Alessandro Cattalini (Author), Ugo de Grazia (Author), Cinzia Cagnoli (Author), Marco de Curtis (Author), Giorgio Stefano Battaglia (Author), Francesca Colciaghi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antiepileptic drug-resistance is a major health problem in patients with cortical dysplasia (CD). Whether drug-resistant epilepsy is associated with progressive brain damage is still debated. We previously generated a rat model of acquired CD, the methylazoxymethanol-pilocarpine (MP) rat, in which t...