Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs

• मुख्य लेखकों: José A. Herrera (लेखक), Christopher S. Ward (लेखक), Meagan R. Pitcher (लेखक), Alan K. Percy (लेखक), Steven Skinner (लेखक), Walter E. Kaufmann (लेखक), Daniel G. Glaze (लेखक), Xander H. T. Wehrens (लेखक), Jeffrey L. Neul (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2015-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

One quarter of deaths associated with Rett syndrome (RTT), an X-linked neurodevelopmental disorder, are sudden and unexpected. RTT is associated with prolonged QTc interval (LQT), and LQT-associated cardiac arrhythmias are a potential cause of unexpected death. The standard of care for LQT in RTT is...