Unveiling Anticancer Potential of COX-2 and 5-LOX Inhibitors: Cytotoxicity, Radiosensitization Potential and Antimigratory Activity against Colorectal and Pancreatic Carcinoma

• Main Authors: Jelena Bošković (Author), Vladimir Dobričić (Author), Otilija Keta (Author), Lela Korićanac (Author), Jelena Žakula (Author), Jelena Dinić (Author), Sofija Jovanović Stojanov (Author), Aleksandar Pavić (Author), Olivera Čudina (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Apart from cytotoxicity, inhibitors of the COX-2 enzyme have demonstrated additional effects important for cancer treatment (such as radiosensitization of tumor cells and cell antimigratory effects); however, the relationship between the inhibition of other inflammation-related enzyme 5-LOX inhibito...