Effect of obesity on early blood-brain barrier disruption following transient focal cerebral ischemia

• 主要な著者: C. Li (著者), Z. Jiang (著者), W. Lu (著者), D. Arrick (著者), K. McCarter (著者), H. Sun (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2016-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Summary Objective We determined the effect of obesity on early post‐ischemic blood-brain barrier (BBB) disruption. Methods Male C57BL/6J mice were fed a high‐fat diet (HFD) or standard chow for 16 weeks. Transient focal cerebral ischemia was induced by directly ligating the middle cerebral artery fo...