Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control

• Main Authors: Jonathan D. Douros (Author), Jingjing Niu (Author), Sophia Sdao (Author), Trillian Gregg (Author), Matthew J. Merrins (Author), Jonathan Campbell (Author), Jenny Tong (Author), David D'Alessio (Author)
• Format: Book
• Published: Elsevier, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Bariatric surgery acutely improves glucose control, an effect that is generally sustained for years in most patients. The acute postoperative glycemic reduction is at least partially mediated by enhanced incretin secretion and islet function, and occurs independent of caloric restriction,...