Preclinical Characterization of Antinociceptive Effect of Bergamot Essential Oil and of Its Fractions for Rational Translation in Complementary Therapy

• Main Authors: Damiana Scuteri (Author), Laura Rombolà (Author), Michele Crudo (Author), Chizuko Watanabe (Author), Hirokazu Mizoguchi (Author), Shinobu Sakurada (Author), Kengo Hamamura (Author), Tsukasa Sakurada (Author), Paolo Tonin (Author), Maria Tiziana Corasaniti (Author), Giacinto Bagetta (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bergamot essential oil (BEO) is endowed with consistent and reproducible antinociceptive and anti-allodynic properties when administered via an inhalation route. However, the effects of its main constituents and of its decolored (DEC) and deterpenated (DET) fractions, which are enriched in limonene...