Macrophage LMO7 deficiency facilitates inflammatory injury via metabolic-epigenetic reprogramming

• Главные авторы: Shixin Duan (Автор), Xinyi Lou (Автор), Shiyi Chen (Автор), Hongchao Jiang (Автор), Dongxin Chen (Автор), Rui Yin (Автор), Mengkai Li (Автор), Yuseng Gou (Автор), Wenjuan Zhao (Автор), Lei Sun (Автор), Feng Qian (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2023-12-01T00:00:00Z.
• Предметы: article
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Inflammatory bowel disease (IBD) is a formidable disease due to its complex pathogenesis. Macrophages, as a major immune cell population in IBD, are crucial for gut homeostasis. However, it is still unveiled how macrophages modulate IBD. Here, we found that LIM domain only 7 (LMO7) was downregulated...