Macrophage LMO7 deficiency facilitates inflammatory injury via metabolic-epigenetic reprogramming

• Main Authors: Shixin Duan (Author), Xinyi Lou (Author), Shiyi Chen (Author), Hongchao Jiang (Author), Dongxin Chen (Author), Rui Yin (Author), Mengkai Li (Author), Yuseng Gou (Author), Wenjuan Zhao (Author), Lei Sun (Author), Feng Qian (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammatory bowel disease (IBD) is a formidable disease due to its complex pathogenesis. Macrophages, as a major immune cell population in IBD, are crucial for gut homeostasis. However, it is still unveiled how macrophages modulate IBD. Here, we found that LIM domain only 7 (LMO7) was downregulated...