Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury

• Main Authors: Qian Xiang (Author), Man Wu (Author), Li Zhang (Author), Wenwei Fu (Author), Jinling Yang (Author), Baojun Zhang (Author), Zhaoqing Zheng (Author), Hong Zhang (Author), Yuanzhi Lao (Author), Hongxi Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitophagy is a crucial process in controlling mitochondrial biogenesis. Balancing mitophagy and mitochondrial functions is required for maintaining cellular homeostasis. In this study, we found that Gerontoxanthone I (GeX1) and Macluraxanthone (McX), xanthone derivatives isolated from Garcinia bract...