Dual effect of aucubin on promoting VEGFR2 mediated angiogenesis and reducing RANKL-induced bone resorption

• Egile Nagusiak: Yulin He (Egilea), Hiotong Kam (Egilea), Xue Wu (Egilea), Qian Chen (Egilea), Simon Ming Yuen Lee (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2023-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Angiogenesis is regarded as a critical role in bone repair and regeneration, involving in pathological bone disorders such as osteoporosis. Aucubin, an iridoid glycoside primarily derived from Eucommia ulmoides, is reported to inhibit osteoclast activity, enhance bone formation a...