Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis

Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis

Early-onset, persistent atopic dermatitis (AD) is proposed as a distinct subgroup that may have specific genotypic features. FLG gene loss-of-function variants are the best known genetic factors contributing to epidermal barrier impairment and eczema severity. In a cohort of 140 Finnish children wit...

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Main Authors: Miia Perälä (Author), Meri Kaustio (Author), Alexander Salava (Author), Eveliina Jakkula (Author), Anna S. Pelkonen (Author), Janna Saarela (Author), Anita Remitz (Author), Mika J. Mäkelä (Author)
Format: Book
Published: Elsevier, 2023-07-01T00:00:00Z.
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