Antagonism of toll-like receptor 2 attenuates the formation and progression of abdominal aortic aneurysm

• Main Authors: Huimin Yan (Author), Bing Cui (Author), Xiaowei Zhang (Author), Xiaoming Fu (Author), Jun Yan (Author), Xiaoxing Wang (Author), Xiaoxi Lv (Author), Zhong Chen (Author), Zhuowei Hu (Author)
• Format: Book
• Published: Elsevier, 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abdominal aortic aneurysm (AAA) is an inflammatory vascular disorder with high mortality. Accumulating evidence shows that toll-like receptor 2 (TLR2) plays a critical role in the regulation of wound-repairing process after tissue injury. We wondered if TLR2 signaling contributed to the pathogenesis...