High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting
Objective: α-cells are the second most prominent cell type in pancreatic islets and are responsible for producing glucagon to increase plasma glucose levels in times of fasting. α-cell dysfunction and inappropriate glucagon secretion occur in both type 1 and type 2 diabetes. Thus, there is growing i...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2017-03-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |