Design, Synthesis and In Vitro Antimicrobial Activity of 6-(1<i>H</i>-Benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-thio-3,4-dihydrothieno[2,3-<i>d</i>]pyrimidines

Design, Synthesis and In Vitro Antimicrobial Activity of 6-(1<i>H</i>-Benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-thio-3,4-dihydrothieno[2,3-<i>d</i>]pyrimidines

The rapid development in bacterial resistance to many groups of known antibiotics forces the researchers to discover antibacterial drug candidates with previously unknown mechanisms of action, one of the most relevant being the inhibition of tRNA (Guanine37-N1)-methyltransferase (TrmD). The discover...

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Main Authors: Sergiy V. Vlasov (Author), Olena D. Vlasova (Author), Hanna I. Severina (Author), Konstantin Yu. Krolenko (Author), Oleksandr V. Borysov (Author), Amjad Ibrahim M. Abu Sharkh (Author), Vitaliy S. Vlasov (Author), Victoriya A. Georgiyants (Author)
Format: Book
Published: MDPI AG, 2021-11-01T00:00:00Z.
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