MTHFR A1298C polymorphisms reduce the risk of congenital heart defects: a meta-analysis from 16 case-control studies

Abstract Background Methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in the hyperhomocysteinemia, which is a risk factor related to the occurrence of congenital heart defect (CHD). However, the association between MTHFR polymorphism and CHD has been inconclusive. Methods We conducted...

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Main Authors: Di Yu (Author), Zhulun Zhuang (Author), Zhongyuan Wen (Author), Xiaodong Zang (Author), Xuming Mo (Author)
Format: Book
Published: BMC, 2017-12-01T00:00:00Z.
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