A clinically feasible algorithm for the parallel detection of glioma‐associated copy number variation markers based on shallow whole genome sequencing

• Main Authors: Shuai Wu (Author), Chenyu Ma (Author), Jiawei Cai (Author), Chenkang Yang (Author), Xiaojia Liu (Author), Chen Luo (Author), Jingyi Yang (Author), Zhang Xiong (Author), Dandan Cao (Author), Hong Chen (Author)
• Format: Book
• Published: Wiley, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Molecular features are incorporated into the integrated diagnostic system for adult diffuse gliomas. Of these, copy number variation (CNV) markers, including both arm‐level (1p/19q codeletion, +7/−10 signature) and gene‐level (EGFR gene amplification, CDKN2A/B homozygous deletion) changes,...