Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis

• Glavni autori: Fabian Krutzek (Autor), Klaus Kopka (Autor), Sven Stadlbauer (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a variety of cancers. Among the immune checkpoints addressed, the programmed death receptor 1 (PD-1) and its ligand PD-L1 are the key targets for an ICI. PD-L1 has especially been proven to be a reproducible biomar...