Microwave-assisted synthesis and bioevaluation of new sulfonamides

• Main Authors: Halise Inci Gul (Author), Cem Yamali (Author), Fatma Yesilyurt (Author), Hiroshi Sakagami (Author), Kaan Kucukoglu (Author), Ilhami Gulcin (Author), Mustafa Gul (Author), Claudiu T. Supuran (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, 4-[5-(4-hydroxyphenyl)-3-aryl-4,5-dihydro-1H-pyrazol-1-yl]benzenesulfonamide derivatives (8-14) were synthesized for the first time by microwave irradiation and their chemical structures were confirmed by 1H NMR, 13C NMR and HRMS. Cytotoxic activities and inhibitory effects on carboni...