Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition.

• Main Authors: Tapan Bhattacharyya (Author), Andrew K Falconar (Author), Alejandro O Luquetti (Author), Jaime A Costales (Author), Mario J Grijalva (Author), Michael D Lewis (Author), Louisa A Messenger (Author), Trang T Tran (Author), Juan-David Ramirez (Author), Felipe Guhl (Author), Hernan J Carrasco (Author), Patricio Diosque (Author), Lineth Garcia (Author), Sergey V Litvinov (Author), Michael A Miles (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Chagas disease, caused by infection with the protozoan Trypanosoma cruzi, remains a serious public health issue in Latin America. Genetically diverse, the species is sub-divided into six lineages, known as TcI-TcVI, which have disparate geographical and ecological distributions. TcII, Tc...